Understanding how evolution affects complex traits in organisms.
Experimental evolution of complex traits
This study is looking at how yeast changes and adapts over time in a lab, which could help us understand the genetic changes behind complex diseases in people and find new ways to tackle health problems as we age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon State University NIH-funded |
| Lab location | 1 site (Corvallis, United States) |
| Project ID | NIH-11090360 on NIH RePORTER |
What this research studies
This research investigates the process of evolution and adaptation in organisms, specifically using a laboratory system of yeast. By observing how these yeast populations evolve in real time under controlled conditions, researchers aim to uncover the genetic and phenotypic changes that occur. The study employs a technique called 'Evolve-and-Resequence' to analyze genetic variation during adaptation, which may provide insights into the underlying causes of complex diseases in humans. This approach could lead to new strategies for combating age-related health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing age-related health declines or complex diseases.
Not a fit: Patients with acute conditions unrelated to age or complex diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new tools and therapies for managing complex diseases associated with aging.
How similar studies have performed: Previous research using similar evolutionary approaches has shown promise in understanding adaptation, suggesting potential for success in this study.
Where this research is happening
Corvallis, United States
- Oregon State University — Corvallis, United States (Active)
Researchers
- Principal investigator: Burke, Molly Kathleen — Oregon State University
- Study coordinator: Burke, Molly Kathleen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.