Understanding how estrogen affects cell signaling through specific RNA molecules.
Analysis of divergent transcripts in estrogen-dependent signaling.
['FUNDING_OTHER'] · TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER AT EL PASO · NIH-10923793
This study is looking at how the hormone estrogen works in breast cancer cells, especially focusing on a special type of RNA that might help control how these cells respond to estrogen, which could lead to better understanding and treatment of related diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER AT EL PASO (nih funded) |
| Locations | 1 site (EL PASO, UNITED STATES) |
| Trial ID | NIH-10923793 on ClinicalTrials.gov |
What this research studies
This research investigates how the hormone estrogen interacts with its receptor in breast cancer cells, focusing on a specific type of RNA called divergent transcripts. These transcripts are believed to play a crucial role in regulating the cellular responses triggered by estrogen. By using advanced cellular and genomic techniques, the study aims to uncover the molecular mechanisms that govern how these transcripts influence estrogen-driven gene expression and cellular activities. This understanding could provide insights into diseases linked to abnormal estrogen signaling.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with estrogen receptor-positive breast cancer or those affected by conditions related to estrogen signaling.
Not a fit: Patients with estrogen receptor-negative breast cancer or those not affected by estrogen-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for breast cancer and other conditions influenced by estrogen signaling.
How similar studies have performed: Previous research has shown promising results in understanding estrogen signaling and its implications in breast cancer, suggesting that this approach has potential for significant findings.
Where this research is happening
EL PASO, UNITED STATES
- TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER AT EL PASO — EL PASO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GADAD, SHRIKANTH — TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER AT EL PASO
- Study coordinator: GADAD, SHRIKANTH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Breast Cancer