Understanding how epithelial tissues develop and respond to injury
Epithelial biology: morphogenesis and damage signaling
This study looks at how the tiny cells that make up our organs, using fruit flies as a model, react to physical forces and injuries, helping us understand how our bodies heal and develop.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-11042149 on NIH RePORTER |
What this research studies
This research investigates the fundamental biology of epithelial tissues, which are essential for organ formation and function. Using the fruit fly Drosophila as a model organism, the research explores how these tissues respond to mechanical forces and damage. By examining the interactions between cells and their surrounding extracellular matrix, the study aims to uncover mechanisms that shape organs and understand the body's response to epithelial injuries. This work combines various scientific approaches to provide insights that could be applicable across different species.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include adults with conditions related to epithelial tissue damage or developmental abnormalities.
Not a fit: Patients with non-epithelial related conditions or those under 21 years old may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for repairing damaged tissues and improving organ function in humans.
How similar studies have performed: Previous research has shown success in understanding epithelial biology and its implications for tissue engineering and repair, indicating that this approach has a solid foundation.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Bilder, David — University of California Berkeley
- Study coordinator: Bilder, David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.