Understanding how epigenetic changes affect development and disease
Official title: Center for Biomedical Research Excellence, Epigenomics of Development and Disease
Funded at University of North Dakota · NIH-10936145 · Data updated 2026-11-12
This study is looking at how certain changes in our genes, which don’t involve changing the DNA itself, can affect our health and development, and it hopes to find new ways to improve treatments for patients dealing with different health issues.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of North Dakota NIH-funded |
| Lab location | 1 site (Grand Forks, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $1,057,500 |
| NIH project number | 1P30GM154634-01 |
| Project ID | NIH-10936145 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include individuals with conditions influenced by epigenetic changes, such as certain cancers or developmental disorders.
✕Less likely to help
Patients with conditions that are not significantly influenced by epigenetic factors may not receive benefit from this research.
What this research studies
This research focuses on the epigenetic mechanisms that influence development and disease processes. By supporting a collaborative group of experts, the project aims to enhance understanding of how genetic expression is regulated without altering the DNA sequence itself. Patients may benefit from advancements in treatments that target these epigenetic changes, potentially leading to new therapeutic strategies. The research involves collecting and analyzing genomic data to uncover insights into various health conditions.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that address the underlying epigenetic factors in diseases.
How similar studies have gone: Previous research in epigenetics has shown promising results, indicating that this approach has the potential for significant breakthroughs in understanding and treating diseases.
Where this research is happening
-
University of North Dakota
Grand Forks, United States Active
Researchers
- Principal investigator: Vaughan, Roxanne a — University of North Dakota
- Study coordinator: Vaughan, Roxanne a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.