Understanding how eosinophils behave in allergic conditions
Official title: Spatial and Temporal Resolution of EosinophilSpecialization in Allergic Microenvironments
Funded at University of Colorado Denver · NIH-10949165 · Data updated 2026-11-12
This study is looking at how a type of white blood cell called eosinophils behaves in allergic reactions, hoping to find new ways to improve treatments for allergies so that patients can feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | August 12, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $468,000 |
| NIH project number | 1DP2AI184728-01 |
| Project ID | NIH-10949165 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from allergic diseases characterized by eosinophilic inflammation.
✕Less likely to help
Patients with non-allergic conditions or those not affected by eosinophilic inflammation may not benefit from this research.
What this research studies
This research investigates the role of eosinophils, a type of white blood cell, in allergic inflammation. It aims to understand how these cells differentiate, interact with surrounding tissues, and survive longer than expected in certain environments. By studying the molecular signals that influence eosinophil behavior, the research seeks to uncover new insights that could improve treatments for allergic diseases. Patients may benefit from a better understanding of how eosinophil-targeting therapies work and why they may not always lead to symptom relief.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for allergic diseases by optimizing eosinophil-targeting therapies.
How similar studies have gone: Previous research has shown promising results in understanding eosinophil behavior, but this specific approach is relatively novel.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Dunn, Julia Louise Malik — University of Colorado Denver
- Study coordinator: Dunn, Julia Louise Malik
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.