Understanding how enzymes keep metabolism balanced
Toward a quantitative understanding of metabolic homeostasis
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA BERKELEY · NIH-11001133
This study is looking at how enzymes help keep our body's energy and building blocks in balance, which is important for everyone, especially those with diabetes, heart issues, or cancer, as it could lead to new treatments to help them feel better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA BERKELEY (nih funded) |
| Locations | 1 site (BERKELEY, UNITED STATES) |
| Trial ID | NIH-11001133 on ClinicalTrials.gov |
What this research studies
This research aims to explore how enzymes regulate metabolic homeostasis, which is crucial for maintaining energy levels and building blocks necessary for cell function. By developing mathematical models and experimental methods, the project seeks to uncover the complex interactions between enzymes and metabolites that contribute to metabolic balance. Patients with conditions like diabetes, cardiovascular diseases, and cancer may benefit from insights gained through this research, as it could lead to new therapeutic strategies. The research will involve both in vitro experiments and live cell studies to validate the models developed.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with metabolic disorders such as diabetes, cardiovascular diseases, or cancer.
Not a fit: Patients with metabolic conditions that are not related to enzyme regulation may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for metabolic disorders that affect millions of patients.
How similar studies have performed: Previous research has shown promise in understanding metabolic pathways, but this approach aims to provide a novel and comprehensive understanding of metabolic homeostasis.
Where this research is happening
BERKELEY, UNITED STATES
- UNIVERSITY OF CALIFORNIA BERKELEY — BERKELEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TITOV, DENIS VASILIEVICH — UNIVERSITY OF CALIFORNIA BERKELEY
- Study coordinator: TITOV, DENIS VASILIEVICH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, Cardiovascular Diseases, cardiovascular disorder