Understanding how environmental factors and stress affect youth suicide risk
Official title: The Role of the Exposome and Allostatic Load in Risk and Resilience to Youth Suicide Attempts
Funded at Children's Hosp of Philadelphia · NIH-10979667 · Data updated 2026-11-12
This study is looking at how things in our environment and our bodies can affect the risk of suicide attempts in young people aged 12 to 20, with the hope of finding ways to help those who are struggling and understand why some kids are able to cope better than others.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $739,843 |
| NIH project number | 1R01MH134886-01A1 |
| Project ID | NIH-10979667 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20 who may be experiencing environmental stressors or mental health challenges.
✕Less likely to help
Patients who are outside the age range of 12 to 20 or do not face significant environmental stressors may not benefit from this research.
What this research studies
This research investigates the complex relationship between environmental factors, biological responses, and the risk of suicide attempts in youth aged 12 to 20. It aims to develop tools to measure adverse environmental exposures and how they contribute to disparities in suicide risk among different populations. By integrating environmental data with biological measures, the study seeks to uncover how stress impacts mental health and resilience in adolescents. The goal is to better understand why some youth who face adversity do not attempt suicide, providing insights into prevention strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for youth at risk of suicide.
How similar studies have gone: Previous research has linked environmental factors and biological responses to suicide risk, but this study's integrated approach is novel and untested.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Barzilay, Ran — Children's Hosp of Philadelphia
- Study coordinator: Barzilay, Ran
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.