Understanding how environmental factors affect gene expression and its implications for health
Investigating ELSI issues that may facilitate or impede clinical translation of epigenomic research
This study is looking at how things in our environment, like pollution and our daily habits, can change our DNA and affect our health, and it aims to help everyone understand this important information better so they can make informed choices about their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10866439 on NIH RePORTER |
What this research studies
This research investigates how environmental factors, such as pollutants and lifestyle choices, can chemically alter DNA and influence gene expression, a field known as epigenetics. It aims to develop effective communication strategies to help diverse populations understand epigenetic information and its clinical implications. The study will explore the ethical, legal, and social implications (ELSI) of epigenetics, focusing on how to prevent harmful beliefs and promote accurate understanding in clinical settings. By addressing these issues, the research seeks to facilitate the translation of epigenetic findings into practical healthcare applications.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse socio-demographic backgrounds who are interested in how environmental factors may affect their health.
Not a fit: Patients who are not interested in or do not have concerns about the impact of environmental factors on their health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could improve patient understanding of epigenetics, leading to better health decisions and reduced stigma associated with genetic conditions.
How similar studies have performed: Other research has shown success in using communication strategies to improve public understanding of complex scientific topics, suggesting that this approach may be effective.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Waters, Erika a — Washington University
- Study coordinator: Waters, Erika a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.