NIH-funded research NIH-funded research

Understanding how environment and lifestyle affect child health in the Northern Plains

Official title: Environmental influences on Child Health Outcomes in the Northern Plains PASS-ECHO Cohort

Funded at Avera Mckennan · NIH-11319124 · Data updated 2026-11-12

This project helps us learn how factors like lifestyle and environment during pregnancy and childhood shape a child's health, especially their weight and brain development.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAvera Mckennan
NIH-funded
Lab location1 site (Sioux Falls, United States)
Project startSeptember 21, 2016
Project endMay 31, 2030
Funding year2025
Award (this year)$5,232,574
NIH project number4UH3OD023279-11
Project IDNIH-11319124 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants include pregnant individuals, mothers and their children, and those planning a pregnancy, particularly from American Indian and rural communities in the Northern Plains.

Less likely to help

Individuals not planning a pregnancy, not currently pregnant, or not within the specified geographic and community focus may not directly benefit from participation in this specific cohort.

What this research studies

We are continuing to follow a large group of mothers and children, called the PASS-ECHO cohort, to understand how different environmental and lifestyle factors impact their health over time. Our goal is to see how things like a mother's stress during pregnancy, or her diet and daily habits, might affect her child's risk for obesity and how their brain develops. We are also inviting new pregnant individuals and those planning a pregnancy to join, with a special focus on including families from American Indian and rural communities.

Why it matters

Potential benefit: If successful, this work could lead to a better understanding of how to prevent childhood obesity and support healthy brain development by identifying key environmental and lifestyle factors.

How similar studies have gone: This project builds upon the successful strategies and strong community relationships established by the PASS-ECHO team since 2016, indicating a proven track record in cohort management and scientific collaboration.

Where this research is happening

  • Avera Mckennan
    Sioux Falls, United States
    Active

Researchers

  • Principal investigator: Elliott, Amy J — Avera Mckennan
  • Study coordinator: Elliott, Amy J

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.