Understanding how emotions and body responses predict substance use relapse after treatment

Interplay of Affect and Physiology in the Real-Time Prediction of Return to Use During Community Reintegration of Substance Users

['FUNDING_R01'] · UNIVERSITY OF RHODE ISLAND · NIH-11077841

This study is looking at how feelings and physical reactions affect people recovering from substance use disorder as they adjust back to everyday life, with the aim of finding ways to help them stay on track and avoid relapse during tough moments.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF RHODE ISLAND (nih funded)
Locations1 site (KINGSTON, UNITED STATES)
Trial IDNIH-11077841 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between emotional states and physiological responses in individuals recovering from substance use disorder (SUD) during their reintegration into the community. By using daily monitoring techniques, such as ecological momentary assessment, the study aims to identify critical moments when individuals are at higher risk of returning to substance use. The goal is to develop tailored interventions that can be delivered in real-time to help prevent relapse, particularly focusing on managing emotional dysregulation. This approach seeks to enhance the support provided to individuals during the vulnerable period following their treatment discharge.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older who have recently completed residential treatment for substance use disorder.

Not a fit: Patients who are not currently in recovery or those who have not undergone treatment for substance use disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective strategies for preventing relapse in individuals recovering from substance use disorder.

How similar studies have performed: Previous research has shown promise in using real-time monitoring and emotional regulation strategies to support individuals in recovery, indicating that this approach could be effective.

Where this research is happening

KINGSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.