Understanding how emotional regulation and brain connectivity affect early signs of psychosis

Developmental Trajectories of Attenuated Psychotic Symptoms: The Roles of Dispositional Emotion Regulation Strategy Use and Neural Connectivity in Pathways to Psychosis

['FUNDING_FELLOWSHIP'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10996787

This study is looking at how managing emotions and brain connections might affect the early signs of psychosis in people who are at a higher risk, with the goal of finding ways to help prevent these symptoms from getting worse.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA-IRVINE (nih funded)
Locations1 site (IRVINE, UNITED STATES)
Trial IDNIH-10996787 on ClinicalTrials.gov

What this research studies

This research investigates how different emotional regulation strategies and brain connectivity patterns influence the development of early psychotic symptoms in individuals at high risk for psychosis. By using advanced imaging techniques like functional MRI, the study aims to identify the neural mechanisms underlying these symptoms and how they evolve over time. The research will also focus on the role of dispositional emotion regulation in shaping these developmental trajectories, providing insights into potential early interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who are identified as being at clinical high risk for psychosis, particularly those experiencing attenuated psychotic symptoms.

Not a fit: Patients who are not at risk for psychosis or who do not exhibit any early signs of psychotic symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved early identification and intervention strategies for individuals at risk of developing psychosis.

How similar studies have performed: Previous research has shown promising results in understanding the neural correlates of psychotic symptoms, suggesting that this approach could yield valuable insights.

Where this research is happening

IRVINE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.