Understanding how emotional regulation and brain connectivity affect early signs of psychosis
Official title: Developmental Trajectories of Attenuated Psychotic Symptoms: The Roles of Dispositional Emotion Regulation Strategy Use and Neural Connectivity in Pathways to Psychosis
Funded at University of California-Irvine · NIH-10996787 · Data updated 2026-11-12
This study is looking at how managing emotions and brain connections might affect the early signs of psychosis in people who are at a higher risk, with the goal of finding ways to help prevent these symptoms from getting worse.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | September 30, 2024 |
| Project end | September 29, 2026 |
| Funding year | 2024 |
| Award (this year) | $45,563 |
| NIH project number | 1F31MH138063-01 |
| Project ID | NIH-10996787 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are identified as being at clinical high risk for psychosis, particularly those experiencing attenuated psychotic symptoms.
✕Less likely to help
Patients who are not at risk for psychosis or who do not exhibit any early signs of psychotic symptoms may not benefit from this research.
What this research studies
This research investigates how different emotional regulation strategies and brain connectivity patterns influence the development of early psychotic symptoms in individuals at high risk for psychosis. By using advanced imaging techniques like functional MRI, the study aims to identify the neural mechanisms underlying these symptoms and how they evolve over time. The research will also focus on the role of dispositional emotion regulation in shaping these developmental trajectories, providing insights into potential early interventions.
Why it matters
Potential benefit: If successful, this research could lead to improved early identification and intervention strategies for individuals at risk of developing psychosis.
How similar studies have gone: Previous research has shown promising results in understanding the neural correlates of psychotic symptoms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Snyder, Madeline — University of California-Irvine
- Study coordinator: Snyder, Madeline
Related research
Other NIH-funded projects on the same topics.
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Digital tracking of emotions and suicidal thoughts for people at high risk for psychosis
This project uses smartphone prompts and sensor data to track emotional changes and moments of suicidal thinking in people at clinical high risk for psychosis.
-
Monitoring emotions and suicidal thoughts in people at risk for psychosis
This study is looking at how young people who are at risk for psychosis handle their emotions and how that might connect to thoughts of suicide, using digital tools to track their feelings in real-time to help find better ways to support them.
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Psychosis in diverse settings across the world
This project studies how psychotic disorders show up and respond to treatment in adults with diverse backgrounds, including populations in Africa, the Caribbean, and other Global South settings.
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Psychosis in Diverse Settings: Understanding Symptoms and Treatment Across Global South
A human-facing study will look at how psychotic disorders present and respond to treatment in adults from Africa, the Caribbean, and other Global South settings, using genetic and clinical data.
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A new online brain-scan-style tool to spot early psychosis risk
A new online-based set of tasks and a computer model aims to identify people at high risk for developing psychosis earlier and more accurately.
-
Genetic clues for early-onset psychosis in Latino youth
This project looks at the genes of young people with early-onset psychosis and compares them with similar youths without psychosis to find genetic factors that contribute to the illness.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.