Understanding how electroconvulsive therapy affects depression and memory
2/4 Deciphering Mechanisms of ECT Outcomes and Adverse Effects (DECODE)
This study is looking at how electroconvulsive therapy (ECT) can help adults with major depression while also checking for any memory issues it might cause, so we can find the best ways to use this treatment and make it safer and more effective for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project ID | NIH-11122203 on NIH RePORTER |
What this research studies
This research investigates the effects of electroconvulsive therapy (ECT) on adults with major depression, focusing on both its antidepressant benefits and potential cognitive side effects like memory loss. The study aims to develop standardized methods for administering ECT and measuring its outcomes, including the use of advanced neuroimaging techniques and cognitive assessments. By integrating various analytical models, the research seeks to identify biomarkers that predict both positive responses to ECT and adverse cognitive effects, ultimately aiming to optimize treatment protocols for better patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing major depression and are considering ECT as a treatment option.
Not a fit: Patients who are not experiencing major depression or those who are not eligible for ECT may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved ECT protocols that maximize antidepressant effects while minimizing cognitive side effects for patients.
How similar studies have performed: Previous research has shown promise in understanding ECT outcomes, but this study aims to take a novel approach by integrating multiple analytical methods to enhance understanding of both efficacy and safety.
Where this research is happening
Albuquerque, United States
- University of New Mexico Health Scis Ctr — Albuquerque, United States (Active)
Researchers
- Principal investigator: Abbott, Christopher C — University of New Mexico Health Scis Ctr
- Study coordinator: Abbott, Christopher C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.