Understanding how electrical stimulation affects brain activity
Interrogating the propagation of electrical stimulation across scales in vivo
This study is looking at how sending electrical signals to the brain can help activate specific groups of brain cells, which could lead to better and more precise treatments for conditions like depression or epilepsy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10795709 on NIH RePORTER |
What this research studies
This research investigates how electrical stimulation of the brain activates different groups of neurons. By using advanced monitoring techniques, the study aims to identify which stimulation patterns are effective and how they propagate through the brain. This could help reduce the trial-and-error process currently used in clinical settings, making treatments more efficient and targeted. The research focuses on understanding the local and widespread effects of stimulation in living animal models, which may eventually translate to human applications.
Who could benefit from this research
Good fit: Ideal candidates for this research would be individuals with neurological disorders that may benefit from electrical brain stimulation therapies.
Not a fit: Patients with conditions that do not involve the need for electrical stimulation of the brain may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for neurological conditions that require electrical brain stimulation.
How similar studies have performed: Previous research has shown promise in understanding brain stimulation effects, but this study aims to provide deeper insights into the mechanisms involved, making it a novel approach.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Denman, Daniel James — University of Colorado Denver
- Study coordinator: Denman, Daniel James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.