Understanding how electrical stimulation affects brain activity
Integrated Biophysical and Neural Model of Electrical Stimulation Effects
This study is exploring how gentle electrical stimulation can wake up certain brain cells, and it's designed for anyone curious about how our brains work, especially during different sleep stages.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10670301 on NIH RePORTER |
What this research studies
This research investigates how electrical stimulation can activate specific neurons in the brain. By developing a computational model, the team aims to predict which neurons will respond to different stimulation protocols based on their shape, location, and connectivity. The study will involve modeling various species, including humans, and examining how factors like sleep stages influence brain activity. Advanced imaging techniques will be used to validate the model's predictions, providing insights into neuronal behavior during stimulation.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with mental health disorders who may benefit from targeted electrical stimulation therapies.
Not a fit: Patients with conditions unrelated to neuronal activity or those who do not respond to electrical stimulation therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for mental health disorders by optimizing electrical stimulation therapies.
How similar studies have performed: Other research has shown promise in using computational models to predict neuronal responses to stimulation, suggesting that this approach could yield valuable insights.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Halgren, Eric — University of California, San Diego
- Study coordinator: Halgren, Eric
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.