Understanding how electric stimulation affects brain cells
Multi-modal, large-scale characterization of cellular and cell-type-specific effects with electric stimulation in rodent and human brain
['FUNDING_R01'] · ALLEN INSTITUTE · NIH-10893366
This study is looking at how electric stimulation can help improve treatments for brain conditions like epilepsy and dementia by exploring its effects on different brain cells in both rodents and humans, so we can find the best ways to use this therapy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALLEN INSTITUTE (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10893366 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of electric stimulation on different types of brain cells to improve treatments for neurological disorders like epilepsy and dementia. By studying both rodent and human brain tissues, the researchers aim to identify the best ways to apply electric stimulation to enhance its effectiveness. The project combines advanced techniques such as in vitro electrophysiology and in vivo recordings to gain insights into the cellular mechanisms involved. This approach seeks to clarify how and when to use electric stimulation for optimal therapeutic outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with neurological disorders such as epilepsy, dementia, or Parkinson’s disease.
Not a fit: Patients with conditions unrelated to neurological disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for neurological disorders, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using electric stimulation for neurological treatments, but this study aims to provide deeper insights into its mechanisms, making it a novel approach.
Where this research is happening
SEATTLE, UNITED STATES
- ALLEN INSTITUTE — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, SOO YEUN — ALLEN INSTITUTE
- Study coordinator: LEE, SOO YEUN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.