Understanding how early skin issues affect allergies in children
SUNBEAM Birth Cohort: Deciphering the role of early life skin dysfunction in development of the allergic march
This study is looking at how skin problems in babies, like eczema, might lead to allergies and asthma later on, and it’s for parents who want to understand why some kids with skin issues develop more allergies while others don’t.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project ID | NIH-10802027 on NIH RePORTER |
What this research studies
This research investigates the connection between early life skin conditions, such as atopic dermatitis, and the development of allergic diseases like food allergies and asthma in children. By examining different biological mechanisms in the skin, the study aims to identify why some infants with skin issues develop further allergies while others do not. The research will utilize both clinical observations and animal models to explore how skin barrier dysfunction and inflammation contribute to allergic responses. This comprehensive approach seeks to uncover the underlying factors that drive the 'allergic march' in young children.
Who could benefit from this research
Good fit: Ideal candidates for this research include infants and young children diagnosed with atopic dermatitis or other skin conditions.
Not a fit: Patients who do not have any history of allergic diseases or skin conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for allergic diseases in children.
How similar studies have performed: Previous research has shown promising results in understanding the links between skin conditions and allergies, but this specific approach to studying the allergic march is relatively novel.
Where this research is happening
Denver, United States
- National Jewish Health — Denver, United States (Active)
Researchers
- Principal investigator: Seibold, Max a — National Jewish Health
- Study coordinator: Seibold, Max a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.