Understanding how early preventive measures can reduce suicide and overdose risks

Collaborative to understand impacts of early preventive interventions on suicide and overdose mortality using data harmonization methodology

NIH-funded research Johns Hopkins University · NIH-11164730

This study is looking at past prevention programs for young people to see if getting help early can reduce the chances of having suicidal thoughts or behaviors, as well as other serious issues like overdoses and accidents, and it aims to find out what parts of these programs work best.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11164730 on NIH RePORTER

What this research studies

This research aims to analyze existing data from large prevention trials conducted before adulthood to see if early interventions can lower the risk of suicidal thoughts and behaviors, as well as related issues like overdose and accidents. By harmonizing and integrating these datasets, the study will explore unexpected benefits of these interventions. The research will utilize advanced analytical methods to identify which aspects of these early interventions are most effective in reducing risks for later life adverse outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who participated in prevention trials before the age of 18 and are at risk for suicidal thoughts or behaviors.

Not a fit: Patients who have not been involved in any early preventive interventions or those who are already experiencing severe suicidal ideation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective early interventions that significantly reduce the risk of suicide and overdose in individuals.

How similar studies have performed: Previous research has shown promising results in using early interventions to mitigate risks for mental health issues, suggesting that this approach may yield significant insights.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.