Understanding how early preventive measures can reduce suicide and overdose risks
Official title: Collaborative to understand impacts of early preventive interventions on suicide and overdose mortality using data harmonization methodology
Funded at Johns Hopkins University · NIH-11164730 · Data updated 2026-11-12
This study is looking at past prevention programs for young people to see if getting help early can reduce the chances of having suicidal thoughts or behaviors, as well as other serious issues like overdoses and accidents, and it aims to find out what parts of these programs work best.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | August 9, 2024 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $2,320,210 |
| NIH project number | 5U01MH137067-02 |
| Project ID | NIH-11164730 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who participated in prevention trials before the age of 18 and are at risk for suicidal thoughts or behaviors.
✕Less likely to help
Patients who have not been involved in any early preventive interventions or those who are already experiencing severe suicidal ideation may not benefit from this research.
What this research studies
This research aims to analyze existing data from large prevention trials conducted before adulthood to see if early interventions can lower the risk of suicidal thoughts and behaviors, as well as related issues like overdose and accidents. By harmonizing and integrating these datasets, the study will explore unexpected benefits of these interventions. The research will utilize advanced analytical methods to identify which aspects of these early interventions are most effective in reducing risks for later life adverse outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more effective early interventions that significantly reduce the risk of suicide and overdose in individuals.
How similar studies have gone: Previous research has shown promising results in using early interventions to mitigate risks for mental health issues, suggesting that this approach may yield significant insights.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Wilcox, Holly C — Johns Hopkins University
- Study coordinator: Wilcox, Holly C
Related research
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A universal school program to help middle schoolers stay emotionally regulated and safer
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.