Understanding how early life factors affect allergies and asthma in children
Identification of Early Metabolomic and Immune Endotypes of Allergy and Asthma: An Integrated Multiomics Approach
['FUNDING_CAREER'] · TRUSTEES OF INDIANA UNIVERSITY · NIH-10904907
This study is looking at how things like diet and environment during pregnancy and early life can affect babies' metabolism and immune systems, helping us understand why some infants might develop allergies and asthma later on.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TRUSTEES OF INDIANA UNIVERSITY (nih funded) |
| Locations | 1 site (BLOOMINGTON, UNITED STATES) |
| Trial ID | NIH-10904907 on ClinicalTrials.gov |
What this research studies
This research investigates how metabolic and immune changes in infants, influenced by environmental factors during pregnancy and early life, contribute to allergies and asthma. By analyzing metabolites and immune responses in infants, the study aims to identify specific patterns that predict the risk of developing wheezing and allergic conditions. The approach combines various biological data to provide a comprehensive view of the underlying mechanisms involved in these conditions, potentially leading to earlier identification and intervention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants and young children who are at risk for developing allergies or asthma due to environmental exposures.
Not a fit: Patients who are older children or adults, or those without a history of allergies or asthma, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and prevention strategies for allergies and asthma in children.
How similar studies have performed: Previous research has shown promise in using integrated omics approaches to understand chronic diseases, suggesting that this method could be effective for studying childhood allergies and asthma.
Where this research is happening
BLOOMINGTON, UNITED STATES
- TRUSTEES OF INDIANA UNIVERSITY — BLOOMINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TURI, KEDIR NESHA — TRUSTEES OF INDIANA UNIVERSITY
- Study coordinator: TURI, KEDIR NESHA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute respiratory infection