Understanding how early life experiences affect child brain development

21/24 Healthy Brain and Child Development National Consortium

NIH-funded research University of Wisconsin-Madison · NIH-10877732

This study is looking at how different environmental factors, like a mother's stress or substance use, can affect how children grow and develop in their first 10 years, and it involves 7,500 mothers and babies from across the U.S. to help find ways to support better health for kids.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison NIH-funded
Lab location1 site (Madison, United States)
Project IDNIH-10877732 on NIH RePORTER

What this research studies

This research investigates the impact of various environmental hazards on child development, focusing on the first 10 years of life. It aims to establish a normative template of developmental trajectories by studying a diverse sample of 7,500 mothers and infants across 24 sites in the United States. Utilizing advanced neuroimaging techniques like MRI and EEG, along with behavioral and physiological assessments, the study seeks to understand how factors such as maternal substance exposure and stress influence neurodevelopment. The findings will contribute to a comprehensive dataset that can be used by the scientific community to improve child health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for participation include mothers and their infants, particularly those who may have experienced environmental hazards during pregnancy or early life.

Not a fit: Patients who are older than 10 years or those without any exposure to the identified environmental hazards may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and interventions for children affected by adverse early life experiences.

How similar studies have performed: Previous research has shown success in understanding child development through similar neuroimaging and behavioral assessment approaches, indicating the potential for impactful findings in this study.

Where this research is happening

Madison, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.