Understanding how early-life cognitive decline relates to late-life Alzheimer's disease
Training in lifespan behavioral, social, and neuroscience research connecting early-life cognitive decline to late-life ADRD
This study is looking at how early signs of thinking and memory problems in kids might be linked to developing Alzheimer's and similar conditions when they're older, with the hope of finding ways to help keep their brains healthy as they age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard University NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-10914126 on NIH RePORTER |
What this research studies
This research investigates the connection between early signs of cognitive decline in children and the development of Alzheimer's disease and related dementias (ADRD) later in life. By analyzing data from a long-term study, researchers aim to identify biomarkers that indicate accelerated brain aging and cognitive decline. The goal is to develop strategies that could potentially slow down the progression of ADRD by understanding how these early indicators relate to brain health in midlife. This approach combines behavioral, social, and neuroscience perspectives to create a comprehensive understanding of aging and cognitive health.
Who could benefit from this research
Good fit: Ideal candidates for this research include children aged 0-11 who may show early signs of cognitive decline or are at risk for developing Alzheimer's disease later in life.
Not a fit: Patients who are already diagnosed with advanced Alzheimer's disease or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to early interventions that prevent or slow the onset of Alzheimer's disease and related dementias.
How similar studies have performed: Previous research has shown promise in identifying early biomarkers for Alzheimer's disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Cambridge, United States
- Harvard University — Cambridge, United States (Active)
Researchers
- Principal investigator: Elliott, Maxwell Lorenz — Harvard University
- Study coordinator: Elliott, Maxwell Lorenz
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.