Understanding how early-life anxiety affects social behavior in primates

ORIGINS AND EMERGENCE OF MALADAPTIVE SOCIOEMOTIONAL BEHAVIOR DURING THE TRANSITION TO ADULTHOOD IN PRIMATES

NIH-funded research University of California at Davis · NIH-10877938

This study looks at how certain early personality traits in young primates can lead to anxiety and depression as they grow up, and it hopes to find new ways to help people with similar issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10877938 on NIH RePORTER

What this research studies

This research investigates the origins of maladaptive socioemotional behavior during the transition to adulthood in nonhuman primates. By studying primates with early-life inhibited temperaments, the research aims to uncover the neurobiological factors that contribute to anxiety and depressive disorders. Utilizing advanced techniques such as neuroimaging and behavioral analysis, the study will track the development of these behaviors over time. The findings could lead to new treatment strategies for anxiety-related conditions.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals with a history of anxiety or depressive disorders, particularly those who exhibited early-life behavioral inhibition.

Not a fit: Patients who do not have a history of anxiety or depressive disorders or those who are not in the relevant age range may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved interventions for anxiety and depressive disorders in both primates and potentially humans.

How similar studies have performed: Other research has shown success in understanding anxiety and depressive disorders through similar longitudinal studies in animal models.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.