Understanding how early immune development affects vaccine response and asthma in children
Administrative Core: IDEAL shapes vaccine response, susceptibility to respiratory infectious disease and asthma
This study is looking at how a child's immune system develops in their early years and how that affects their reactions to vaccines and their chances of getting respiratory illnesses or asthma, with the goal of finding better ways to keep kids healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11051817 on NIH RePORTER |
What this research studies
This research investigates how immune development in early childhood influences responses to vaccines and susceptibility to respiratory diseases and asthma. It employs a combination of advanced computational methods, epigenetic analysis, and laboratory experiments to identify specific immune profiles that correlate with these health outcomes. By integrating findings from various studies, the project aims to enhance our understanding of childhood immune responses and improve health strategies for young patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are children, particularly those with a history of respiratory infections or asthma.
Not a fit: Patients who are adults or do not have respiratory diseases or asthma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccine strategies and interventions for respiratory diseases and asthma in children.
How similar studies have performed: Previous research has shown promising results in understanding immune responses in childhood, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Levy, Ofer — Boston Children's Hospital
- Study coordinator: Levy, Ofer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.