Understanding how dynein helps transport materials in cells
Regulation of Dynein-Mediated Transport
This study is looking at how a tiny motor in our cells called dynein helps move important materials around, which is key for keeping our cells healthy and organized, and it could help us understand more about certain health issues that affect our development and aging.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project ID | NIH-11092693 on NIH RePORTER |
What this research studies
This research investigates the role of dynein, a molecular motor, in transporting various cargoes within cells, which is crucial for maintaining cellular organization and function. By examining how dynein operates during different stages of the cell cycle and in various cell types, the research aims to uncover its impact on tissue architecture and overall health. The study employs advanced techniques to observe dynein's behavior and its effects on cellular processes, which could lead to insights into developmental disorders and degenerative diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with developmental disorders or degenerative diseases that affect motor neuron function and cellular organization.
Not a fit: Patients with conditions unrelated to cellular transport mechanisms or those not experiencing developmental or degenerative disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cellular transport mechanisms, potentially leading to new treatments for conditions related to cellular organization and function.
How similar studies have performed: Previous research has shown promising results in understanding the role of molecular motors like dynein in cellular processes, indicating that this approach has potential for significant findings.
Where this research is happening
Fort Collins, United States
- Colorado State University — Fort Collins, United States (Active)
Researchers
- Principal investigator: Markus, Steven M — Colorado State University
- Study coordinator: Markus, Steven M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.