Understanding how drugs affect mothers and children

Pharmacometrics and Clinical Trial Design Core

['FUNDING_P30'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-10892087

This study is working to make medications safer and more effective for moms and kids by creating better ways to predict how these drugs work in their bodies, so we can fill in the gaps in our knowledge and improve treatment guidelines.

Quick facts

Phase['FUNDING_P30']
Study typeNih_funding
SexAll
SponsorINDIANA UNIVERSITY INDIANAPOLIS (nih funded)
Locations1 site (INDIANAPOLIS, UNITED STATES)
Trial IDNIH-10892087 on ClinicalTrials.gov

What this research studies

This research focuses on improving drug therapy for mothers and children by developing advanced models that predict how drugs behave in these populations. It combines expertise in pharmacometrics and clinical trial design to analyze data from various studies, including in vitro and clinical trials. The goal is to create guidelines that ensure high-quality data and to identify knowledge gaps in drug responses during pregnancy and childhood. By integrating data from multiple sources, the research aims to enhance our understanding of how individual differences affect drug efficacy and safety.

Who could benefit from this research

Good fit: Ideal candidates for this research include pregnant women, lactating mothers, and children up to 21 years old who may require medication.

Not a fit: Patients who are not pregnant, lactating, or within the pediatric age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective drug therapies for mothers and children.

How similar studies have performed: Previous research has shown success in using pharmacometric models to improve drug therapies in pediatric populations, indicating a promising approach.

Where this research is happening

INDIANAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.