Understanding how drug-resistant infections spread in nursing homes
Official title: Genomics of MDRO Transmission in Nursing Homes
Funded at University of California-Irvine · NIH-11119002 · Data updated 2026-11-12
This study is looking at how germs that are hard to treat spread in nursing homes, so we can find better ways to keep residents safe and healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | July 11, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $396,017 |
| NIH project number | 5U19AI172725-03 |
| Project ID | NIH-11119002 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are residents of nursing homes who may be at risk for multidrug-resistant infections.
✕Less likely to help
Patients who are not in nursing homes or those who do not have risk factors for MDRO infections may not benefit from this research.
What this research studies
This research investigates the transmission patterns of multidrug-resistant organisms (MDROs) in nursing homes, which are critical environments for the spread of these infections. By using genomic data, the study aims to identify how these pathogens are transmitted among residents and from the environment, helping to pinpoint effective control measures. The approach includes assessing various factors such as human and environmental reservoirs that contribute to the spread of MDROs. This comprehensive analysis will provide insights necessary for developing targeted interventions to reduce infection rates in these facilities.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of drug-resistant infections in nursing homes, improving patient health outcomes.
How similar studies have gone: Previous research has shown that genomic surveillance can effectively track and control the spread of infections in healthcare settings, indicating a promising approach for this study.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Earl, Ashlee Miriam — University of California-Irvine
- Study coordinator: Earl, Ashlee Miriam
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.