Understanding how Down syndrome affects health and disease risk
Integrating Imaging-based Infrastructure into the INCLUDE Data Hub
This study is looking at how Down syndrome affects health, especially the higher chances of developing Alzheimer's and other health issues, to help us understand why this happens and find ways to improve health for people with Down syndrome.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11194082 on NIH RePORTER |
What this research studies
This research investigates the unique health profile of individuals with Down syndrome, focusing on their increased risk for conditions like Alzheimer's disease and other comorbidities. By examining genetic, epigenetic, and environmental factors, the study aims to uncover the mechanisms that influence how Down syndrome manifests in different individuals. The research utilizes advanced imaging techniques and data integration to better understand these relationships and improve health outcomes for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with Down syndrome, particularly those under 11 years old, who may be at risk for Alzheimer's disease and other related conditions.
Not a fit: Patients without Down syndrome or those who do not have related comorbidities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for individuals with Down syndrome and related conditions.
How similar studies have performed: Previous research has shown promising results in understanding the health profiles of individuals with Down syndrome, indicating that this approach may yield valuable insights.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Resnick, Adam Cain — Children's Hosp of Philadelphia
- Study coordinator: Resnick, Adam Cain
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.