Understanding how dopamine helps animals navigate using smell

Investigating dopamine's role in olfactory navigation

NIH-funded research Weill Medical Coll of Cornell Univ · NIH-11242308

This study looks at how a brain chemical called dopamine helps fruit flies find their way through tricky smells, so researchers can learn more about how our brains make decisions based on what we smell.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionWeill Medical Coll of Cornell Univ NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11242308 on NIH RePORTER

What this research studies

This research investigates the role of dopamine in helping animals, specifically fruit flies, navigate through complex odor environments. By studying the neural circuits in Drosophila melanogaster, researchers aim to understand how dopamine influences decision-making and behavior during olfactory navigation. The project utilizes advanced genetic techniques to explore how dopamine neurons interact with other brain cells to facilitate tracking of odor plumes. This approach allows for a detailed examination of the molecular and circuit-level mechanisms involved in this essential sensory process.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals interested in the neurological basis of sensory processing and those affected by conditions that impair olfactory function.

Not a fit: Patients with no interest in sensory processing or those not affected by olfactory disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of sensory navigation, potentially leading to new treatments for disorders related to sensory processing.

How similar studies have performed: Previous studies have shown success in using Drosophila as a model for understanding neural mechanisms, indicating that this approach is promising.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.