Understanding how dopamine circuits influence methamphetamine addiction
Dopamine Neuronal Microcircuits Controlling Methamphetamine Seeking Behavior
This study is looking at how tiny circuits in the brain that use dopamine affect the way people seek out methamphetamine, and it aims to find new ways to understand and treat addiction, which could help those struggling with it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project ID | NIH-11000863 on NIH RePORTER |
What this research studies
This research investigates the role of dopamine microcircuits in the brain that control behaviors related to seeking methamphetamine. Using advanced techniques such as mouse models and electrophysiology, the study aims to uncover how dopamine neurotransmission in specific brain areas affects addiction behaviors. The research also includes training in various scientific methodologies, which will help develop new strategies for understanding and potentially treating addiction. Patients may benefit from insights gained about the biological mechanisms underlying their addiction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are experiencing addiction to methamphetamine or have a history of methamphetamine use.
Not a fit: Patients who are not addicted to methamphetamine or who have not engaged in substance use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for individuals struggling with methamphetamine addiction.
How similar studies have performed: Previous research has shown promising results in understanding addiction through similar neurobiological approaches, indicating potential for success in this area.
Where this research is happening
Amherst, United States
- State University of New York at Buffalo — Amherst, United States (Active)
Researchers
- Principal investigator: Dominguez Lopez, Sergio — State University of New York at Buffalo
- Study coordinator: Dominguez Lopez, Sergio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.