Understanding how DNA variations affect traits

Modeling non-additive genetic mechanisms for complex traits

['FUNDING_OTHER'] · UNIVERSITY OF FLORIDA · NIH-10939650

This study is exploring how changes in our DNA can affect our physical traits, and it's designed to help scientists create new tools that can better understand these connections, making it easier to see how our genes influence things like height or eye color.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF FLORIDA (nih funded)
Locations1 site (GAINESVILLE, UNITED STATES)
Trial IDNIH-10939650 on ClinicalTrials.gov

What this research studies

This research focuses on how differences in DNA sequences can lead to variations in physical traits. By utilizing advanced technologies and large databases, the project aims to create new computational tools that can analyze complex genetic data. These tools will help predict how specific genetic variations influence traits and identify important genes and their interactions. The research combines mathematical modeling with machine learning to improve the accuracy of these predictions and uncover new genetic mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with complex genetic traits or those interested in genetic studies related to their health.

Not a fit: Patients with purely environmental or non-genetic conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prediction of complex traits, which may improve personalized medicine approaches.

How similar studies have performed: Previous research has shown promise in using machine learning and Bayesian methods for genetic analysis, indicating a strong potential for success in this approach.

Where this research is happening

GAINESVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.