Understanding how DNA packaging affects cell division.
Analysis of chromatin-RNA interactions during the cell cycle.
This study looks at how DNA and RNA work together during cell division to help keep our cells healthy and functioning properly, focusing on the important roles of different proteins and RNAs in organizing our genetic material.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10994592 on NIH RePORTER |
What this research studies
This research investigates the interactions between chromatin and RNA during the cell cycle, focusing on how DNA is organized and packaged within the nucleus. It explores the roles of various proteins and RNAs in modifying chromatin structure, which is crucial for proper cell division and function. By examining these interactions, the research aims to uncover the mechanisms that regulate gene expression and chromosome behavior during critical phases of the cell cycle.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancers that may be influenced by chromatin structure and gene expression changes.
Not a fit: Patients with non-cancerous conditions or those not affected by chromatin-related mechanisms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into cancer biology and potential therapeutic targets for cancer treatment.
How similar studies have performed: Previous research has shown promising results in understanding chromatin dynamics and their implications in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Blower, Michael Demian — Boston University Medical Campus
- Study coordinator: Blower, Michael Demian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.