Understanding how DNA modifications affect plant development

Function and Mechanisms of Epigenetic Stability and Dynamics in Arabidopsis

NIH-funded research Whitehead Institute for Biomedical Res · NIH-10890136

This study looks at how changes to DNA in the plant Arabidopsis thaliana help control its growth and development, which could teach us more about how similar processes work in other living things.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWhitehead Institute for Biomedical Res NIH-funded
Lab location1 site (Cambridge, United States)
Project IDNIH-10890136 on NIH RePORTER

What this research studies

This research investigates the role of epigenetic modifications, specifically DNA methylation, in regulating genome function during the development of the plant Arabidopsis thaliana. By examining how DNA methylation influences gene expression and the behavior of transposable elements, the research aims to uncover the mechanisms that maintain a stable epigenetic state. The study utilizes advanced genetic techniques to analyze how these processes are balanced over time and across generations, providing insights into plant biology that may have broader implications for understanding similar mechanisms in other organisms.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include agricultural scientists, plant biologists, and farmers interested in crop improvement.

Not a fit: Patients with no interest or involvement in plant biology or agriculture may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved agricultural practices by enhancing our understanding of plant genetics and development.

How similar studies have performed: Other research has shown success in understanding epigenetic mechanisms in various organisms, suggesting that this approach may yield valuable insights.

Where this research is happening

Cambridge, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancers
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.