Understanding how DNA is copied in humans and viruses

DNA Replication Machines: Structure-Function Studies

NIH-funded research University of Nebraska Medical Center · NIH-11005058

This study is looking at how DNA copies itself in both humans and the herpes virus, with the hope that understanding this better will help create new treatments for diseases caused by DNA mistakes or viral infections, ultimately benefiting patients like you.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Nebraska Medical Center NIH-funded
Lab location1 site (Omaha, United States)
Project IDNIH-11005058 on NIH RePORTER

What this research studies

This research investigates the mechanisms of DNA replication in humans and the herpes simplex virus. By studying the structure and function of key proteins involved in DNA replication, the project aims to uncover how these processes work at a molecular level. The findings could lead to new therapies for diseases caused by errors in DNA replication or viral infections. Patients may benefit from advancements in treatment options that arise from this fundamental understanding.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit would include individuals with conditions related to DNA replication errors or herpes simplex virus infections.

Not a fit: Patients with unrelated health conditions or those not affected by DNA replication disorders or viral infections may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to novel therapies for a variety of diseases, including cancer and viral infections.

How similar studies have performed: Other research has shown success in understanding DNA replication mechanisms, suggesting that this approach could yield valuable insights.

Where this research is happening

Omaha, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions anti-cancerDiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.