Understanding how DNA is copied in humans and viruses
Official title: DNA Replication Machines: Structure-Function Studies
Funded at University of Nebraska Medical Center · NIH-11005058 · Data updated 2026-11-12
This study is looking at how DNA copies itself in both humans and the herpes virus, with the hope that understanding this better will help create new treatments for diseases caused by DNA mistakes or viral infections, ultimately benefiting patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | January 1, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $455,895 |
| NIH project number | 5R35GM152032-02 |
| Project ID | NIH-11005058 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit would include individuals with conditions related to DNA replication errors or herpes simplex virus infections.
✕Less likely to help
Patients with unrelated health conditions or those not affected by DNA replication disorders or viral infections may not receive any benefit from this research.
What this research studies
This research investigates the mechanisms of DNA replication in humans and the herpes simplex virus. By studying the structure and function of key proteins involved in DNA replication, the project aims to uncover how these processes work at a molecular level. The findings could lead to new therapies for diseases caused by errors in DNA replication or viral infections. Patients may benefit from advancements in treatment options that arise from this fundamental understanding.
Why it matters
Potential benefit: If successful, this research could lead to novel therapies for a variety of diseases, including cancer and viral infections.
How similar studies have gone: Other research has shown success in understanding DNA replication mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Nebraska Medical Center
Omaha, United States Active
Researchers
- Principal investigator: Tahirov, Tahir H — University of Nebraska Medical Center
- Study coordinator: Tahirov, Tahir H
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.