Understanding how DNA differences affect health traits
Modeling non-additive genetic mechanisms for complex traits
['FUNDING_OTHER'] · UNIVERSITY OF FLORIDA · NIH-11166421
This project aims to create new computer tools to better understand how our DNA influences complex health conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-11166421 on ClinicalTrials.gov |
What this research studies
Our bodies are shaped by many genes working together, and this project wants to uncover these complex relationships. We are developing advanced computer programs that can look at vast amounts of genetic information from human biobanks. These tools will help us predict how different DNA combinations might lead to certain traits or conditions. Ultimately, this work seeks to reveal the hidden ways genes interact to influence our health.
Who could benefit from this research
Good fit: Patients with complex genetic conditions, or those whose families have such conditions, could eventually benefit from the insights gained from this research.
Not a fit: Patients seeking immediate new treatments or direct clinical care will not receive direct benefit from this foundational research.
Why it matters
Potential benefit: If successful, this work could lead to a much clearer understanding of how genes contribute to complex diseases, potentially guiding future personalized treatments.
How similar studies have performed: This project focuses on developing novel Bayesian and machine learning methods, building upon existing computational genetics approaches.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHOU, JUANNAN — UNIVERSITY OF FLORIDA
- Study coordinator: ZHOU, JUANNAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.