Understanding how DNA damage affects aging and health
Official title: Minnesota Nathan Shock Center of Excellence on Genome Integrity and Aging
Funded at University of Minnesota · NIH-11117546 · Data updated 2026-11-12
This study is looking at how damage to our DNA affects aging and related health issues, and it invites people to join in to help us learn more about how our bodies respond to this damage and what we can do to slow down the aging process.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | June 17, 2025 |
| Project end | May 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $1,270,502 |
| NIH project number | 1P30AG092751-01 |
| Project ID | NIH-11117546 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include individuals over 100 years old or those experiencing accelerated aging symptoms.
✕Less likely to help
Patients with no signs of aging-related DNA damage or those under 100 years old may not benefit from this research.
What this research studies
This research investigates the relationship between DNA damage and the aging process, focusing on how genomic instability contributes to various aging-related conditions. It aims to measure and characterize DNA damage and the body's response to it, which can lead to cellular senescence and other health issues. The study will utilize both human and mouse models to explore the effects of DNA repair mechanisms and identify potential interventions to mitigate aging effects. Patients may have the opportunity to participate in assessments that could help understand their own biological aging.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for reducing age-related health issues and improving longevity.
How similar studies have gone: Previous research has shown promising results in understanding the role of DNA damage in aging, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Robbins, Paul D. — University of Minnesota
- Study coordinator: Robbins, Paul D.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.