Understanding how DNA changes affect organism traits using yeast

Comparative Functional Genomics of Yeast

['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-10443577

This study is looking at how changes in DNA affect the traits of yeast, which could help us understand genetics better and eventually lead to new treatments for genetic disorders that might help patients like you.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorSTANFORD UNIVERSITY (nih funded)
Locations1 site (STANFORD, UNITED STATES)
Trial IDNIH-10443577 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between DNA sequences and the traits of organisms, specifically focusing on yeast. By using advanced genetic techniques, the researchers will disrupt specific genes in various yeast species to observe the resulting changes in their characteristics. This approach aims to create a comprehensive map of genetic interactions and their effects on fitness across related organisms. Patients may benefit from insights gained about genetic functions that could inform future treatments for genetic disorders.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would be individuals with genetic disorders or those interested in genetic research.

Not a fit: Patients with conditions unrelated to genetic mutations or those not interested in genetic research may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of genetic disorders and lead to improved therapies for patients with genetic conditions.

How similar studies have performed: Other research has successfully utilized similar genetic mapping approaches in model organisms, indicating potential for success in this study.

Where this research is happening

STANFORD, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.