Understanding how disordered proteins interact with cell membranes
Structure and Function of Protein Disorder in Membrane Trafficking and Organization
['FUNDING_OTHER'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-10833590
This study is looking at how certain flexible proteins in our cells help with moving and organizing things around, which could lead to new treatments for patients by improving our understanding of how cells work.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10833590 on ClinicalTrials.gov |
What this research studies
This research investigates the role of intrinsically disordered proteins (IDPs) in the processes of membrane trafficking and organization within cells. By examining how these proteins, which lack a stable structure, can still perform essential biological functions, the research aims to uncover the mechanisms behind their interactions with cell membranes. The study employs a combination of laboratory techniques to analyze these interactions and their implications for cellular processes, particularly focusing on a specific protein called complexin. Patients may benefit from insights gained into cellular functions that could lead to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with conditions linked to cellular dysfunction, such as neurodegenerative diseases.
Not a fit: Patients with conditions unrelated to cellular processes or membrane trafficking may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases related to cellular dysfunction and membrane trafficking.
How similar studies have performed: Previous research has shown promising results in understanding the roles of disordered proteins in cellular functions, indicating that this approach has potential for success.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ELIEZER, DAVID — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: ELIEZER, DAVID
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.