Understanding how diseases change quickly
Genomics of rapid adaptation in the lab and in the wild
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-11087569
This project looks at how diseases like cancer and infections can change and adapt over time, using different models to learn more about their evolution.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11087569 on ClinicalTrials.gov |
What this research studies
This project explores how living things, including diseases, adapt rapidly to new conditions. Researchers are studying how yeast adapt to new environments, how fruit flies change with the seasons, and how lung cancer grows and evolves in mice. By looking at these different examples, the goal is to build a better understanding of how evolution works quickly. This knowledge could help us understand how drug resistance develops in infections or how cancers become harder to treat.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation at this stage.
Not a fit: Patients seeking immediate clinical interventions would not directly benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could provide a deeper understanding of how diseases like cancer and infectious agents evolve, potentially leading to new strategies for treatment or prevention.
How similar studies have performed: While the specific approach of integrating diverse systems for a unified theory of adaptation is novel, individual components like experimental evolution in yeast and Drosophila, and mouse models of cancer, are well-established research methods.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PETROV, DMITRI — STANFORD UNIVERSITY
- Study coordinator: PETROV, DMITRI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, Communicable Diseases, Infectious Diseases