NIH-funded research R01 grant

Understanding how different types of touch affect feelings of pleasure and pain relief

Official title: Dynamic Evaluation of Neural Mechanisms for Affective Touch: Pathways for Touch-induced Pleasantness and Pain Modulation

Funded at University of California, San Diego · NIH-11037957 · Data updated 2026-11-12

This study is exploring how different types of touch, like gentle stroking and firm pressure, can help people feel better and relieve pain, so if you're curious about how massage therapy works and want to contribute to improving pain management, this research might be for you!

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startMay 3, 2023
Project endFebruary 29, 2028
Funding year2025
Award (this year)$602,855
NIH project number5R01AT012048-03
Project IDNIH-11037957 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults over 21 years old who experience chronic pain or are interested in the effects of touch therapies.

Less likely to help

Patients who do not experience chronic pain or have conditions that contraindicate touch therapies may not benefit from this research.

What this research studies

This research investigates how light stroking and deep pressure, which are key components of massage therapy, influence feelings of pleasure and pain relief. By examining the roles of specific nerve fibers in the skin, the study aims to uncover the neural mechanisms behind the effects of touch. Participants may experience various forms of touch while researchers analyze their responses using advanced techniques, including machine learning, to better understand how these sensations are processed in the brain. The ultimate goal is to enhance therapeutic approaches for chronic pain management through a deeper understanding of affective touch.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies and enhanced therapeutic techniques for individuals suffering from chronic pain.

How similar studies have gone: Previous research has shown promising results in understanding the effects of touch on pain modulation, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Case, Laura K — University of California, San Diego
  • Study coordinator: Case, Laura K

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.