Understanding how different types of streptococci bacteria interact with harmful pathogens in the mouth
Probing the role of heterogeneity in streptococcal interactions
This study is looking at how different types of common bacteria in your mouth interact with harmful germs that can lead to gum disease, with the goal of finding new ways to improve oral health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10886676 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between various strains of streptococci, which are common bacteria found in the human mouth, and harmful pathogens that can cause oral diseases. By examining the genetic and functional differences among these streptococci, the study aims to uncover how these variations influence the behavior of pathogenic bacteria, such as those linked to chronic periodontitis. The research employs advanced genomic and transcriptomic techniques to analyze these interactions, which could lead to new insights into oral health and disease progression.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic periodontitis or other oral health issues related to bacterial infections.
Not a fit: Patients without any oral health issues or those not harboring significant bacterial populations in their mouths may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating oral diseases by targeting specific bacterial interactions.
How similar studies have performed: Previous research has shown promising results in understanding bacterial interactions in oral health, suggesting that this approach could yield valuable insights.
Where this research is happening
Cleveland, United States
- Case Western Reserve University — Cleveland, United States (Active)
Researchers
- Principal investigator: Lewin, Gina — Case Western Reserve University
- Study coordinator: Lewin, Gina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.