Understanding how different types of streptococci affect oral infections
Probing the role of heterogeneity in streptococcal interactions
['FUNDING_OTHER'] · CASE WESTERN RESERVE UNIVERSITY · NIH-10841244
This study looks at how different types of common mouth bacteria interact with harmful germs that can cause oral diseases, hoping to find new ways to improve our understanding of conditions like gum disease, which could help patients in the future.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CASE WESTERN RESERVE UNIVERSITY (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-10841244 on ClinicalTrials.gov |
What this research studies
This research investigates the interactions between various strains of streptococci, which are common bacteria in the mouth, and harmful oral pathogens. By examining how genetic and phenotypic differences among streptococci influence their behavior and the severity of oral diseases, the study aims to uncover new insights into infection dynamics. The research employs advanced techniques to analyze these microbial interactions and their implications for oral health. Patients may benefit from a better understanding of how these bacteria contribute to conditions like periodontitis.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing chronic oral diseases, particularly periodontitis.
Not a fit: Patients with no oral health issues or those not affected by streptococcal-related infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating oral infections.
How similar studies have performed: Previous research has shown that understanding microbial interactions can lead to significant advancements in treating oral diseases, suggesting this approach has potential for success.
Where this research is happening
CLEVELAND, UNITED STATES
- CASE WESTERN RESERVE UNIVERSITY — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEWIN, GINA — CASE WESTERN RESERVE UNIVERSITY
- Study coordinator: LEWIN, GINA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.