Understanding how different types of proprioceptors develop and function
Molecular Dissection of Proprioceptor Subclass Identity
This study looks at special sensors in our muscles that help us know where our body is and how it's moving, and it aims to find ways to improve treatments for people with movement disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11049403 on NIH RePORTER |
What this research studies
This research investigates the development and function of proprioceptors, which are sensory receptors that provide feedback about body position and movement. It focuses on two main types of proprioceptors found in muscles: muscle spindles and Golgi tendon organs. By examining how these receptors develop and communicate information about muscle length and tension, the research aims to enhance our understanding of movement control. Patients may benefit from insights that could lead to improved treatments for movement disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include adults over 21 years old who may have movement disorders or are interested in the biological mechanisms of proprioception.
Not a fit: Patients with conditions unrelated to proprioception or movement control may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatments for conditions affecting movement and coordination.
How similar studies have performed: Other research has shown success in understanding sensory systems, but this specific focus on proprioceptor subclass identity is relatively novel.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: De Nooij, Joriene — Columbia University Health Sciences
- Study coordinator: De Nooij, Joriene
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.