Understanding how different types of memory affect schizophrenia

A data-driven reconceptualization of the RDoC construct of working memory: Neural correlates of underlying factors and implications for schizophrenia

['FUNDING_R01'] · STATE UNIVERSITY NEW YORK STONY BROOK · NIH-10775702

This study is looking at how different thinking skills, like paying attention and remembering things, affect working memory in people with schizophrenia, with the goal of finding better treatments based on what we learn about the brain.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorSTATE UNIVERSITY NEW YORK STONY BROOK (nih funded)
Locations1 site (STONY BROOK, UNITED STATES)
Trial IDNIH-10775702 on ClinicalTrials.gov

What this research studies

This research investigates the various cognitive abilities that contribute to working memory deficits in patients with schizophrenia. It aims to identify distinct factors such as attentional control and memory retrieval that may be impaired in different patients. By using advanced imaging techniques, the study seeks to uncover the neural correlates of these cognitive abilities, which could lead to more targeted and effective treatments. The approach emphasizes a data-driven analysis to better understand the complexities of working memory in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with schizophrenia who experience working memory deficits.

Not a fit: Patients without a diagnosis of schizophrenia or those who do not exhibit working memory issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for cognitive deficits in schizophrenia, enhancing patients' functional outcomes.

How similar studies have performed: Previous research has shown promise in understanding cognitive deficits in schizophrenia, but this study aims to provide a novel and more nuanced approach.

Where this research is happening

STONY BROOK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.