Understanding how different tumor cell types affect gastric cancer progression and treatment resistance
Tumor cell lineage diversity and composition in gastric cancer progression and therapy resistance
['FUNDING_R01'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-10888167
This study is looking at the different types of cells in stomach cancer to understand why some tumors are tough to treat and grow quickly, which could help find better treatments for people with this cancer.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10888167 on ClinicalTrials.gov |
What this research studies
This research investigates the diversity of tumor cell lineages in gastric adenocarcinoma, a highly aggressive form of cancer. By analyzing individual tumor cells, the study aims to uncover how variations in these cells contribute to the cancer's ability to resist treatment and progress rapidly. The researchers will explore the non-genetic factors that influence tumor behavior and how these factors relate to patient outcomes. This work could lead to new insights into more effective treatment strategies for patients with gastric cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with gastric adenocarcinoma, particularly those experiencing treatment resistance or metastatic disease.
Not a fit: Patients with non-cancerous conditions or those with early-stage gastric cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and better survival rates for patients with gastric adenocarcinoma.
How similar studies have performed: Other research has shown promising results in understanding tumor heterogeneity and its impact on treatment outcomes, suggesting that this approach could yield valuable insights.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TX MD ANDERSON CAN CTR — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, LINGHUA — UNIVERSITY OF TX MD ANDERSON CAN CTR
- Study coordinator: WANG, LINGHUA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Biology, Cancer Treatment, Cancers