Understanding how different species' brains communicate and process signals.
Official title: Origin of Cortical Species-specific Distinctions
Funded at Yale University · NIH-11015110 · Data updated 2026-11-12
This study is exploring how different animals' brains work and communicate, especially looking at a specific part of the brain that might help us understand how we think and feel pain, which could lead to better treatments for brain disorders.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $602,543 |
| NIH project number | 4R37DA023999-16 |
| Project ID | NIH-11015110 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include individuals with cognitive impairments or chronic pain conditions.
✕Less likely to help
Patients with acute pain or those not experiencing cognitive issues may not receive direct benefits from this research.
What this research studies
This research investigates the unique ways in which different species' brains process information and communicate through biological signals. By focusing on the role of cannabinoid receptors, particularly the CB1 receptor, the study aims to uncover the mechanisms behind cognitive functions and pain perception in the brain. The research employs advanced techniques to analyze cellular communication and signaling pathways, which could lead to new insights into brain development and function. Patients may benefit from a better understanding of brain disorders and potential new treatments.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for cognitive and pain-related disorders.
How similar studies have gone: Previous research has shown promising results in understanding cannabinoid receptors and their role in brain function, indicating potential for success in this area.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Rakic, Pasko — Yale University
- Study coordinator: Rakic, Pasko
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.