Understanding how different skin areas behave and respond to conditions
Molecular mechanisms controlling skin heterogeneity
This study is looking at how different parts of your skin, like how thick or pigmented they are, respond to injuries and conditions like acne and hair loss, with the hope of finding better treatments for these issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10889041 on NIH RePORTER |
What this research studies
This research investigates the unique characteristics of various skin regions, such as thickness and pigmentation, and how these differences affect responses to injuries and diseases like acne and androgenetic alopecia. By analyzing skin samples from different areas, researchers will use advanced techniques like single-cell RNA sequencing and chromatin analysis to identify the molecular factors that contribute to skin heterogeneity. The goal is to uncover how these factors are established during development and maintained throughout life, which could lead to better treatments for skin conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with skin conditions such as acne or androgenetic alopecia, particularly those over 21 years old.
Not a fit: Patients with skin conditions not related to regional characteristics or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for skin conditions that vary by region, enhancing patient care.
How similar studies have performed: While the specific molecular mechanisms of skin heterogeneity are not extensively studied, related research has shown promise in understanding skin responses to various conditions.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Millar, Sarah E. — Icahn School of Medicine at Mount Sinai
- Study coordinator: Millar, Sarah E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.