Understanding how different nicotine levels in e-liquids affect user exposure to harmful substances
Official title: Developing Evidence To Inform Regulatory Policy On Nicotine Content In E-Liquids
Funded at Rochester Institute of Technology · NIH-11045749 · Data updated 2026-11-12
This study is looking at how different levels of nicotine in e-liquids affect the health of e-cigarette users, by tracking 120 people over a week to see how much nicotine they use and what it means for their health, so we can better understand the risks of using lower versus higher nicotine options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rochester Institute of Technology NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $742,204 |
| NIH project number | 5R01DA057687-02 |
| Project ID | NIH-11045749 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adult e-cigarette users who regularly consume either low or high nicotine e-liquids.
✕Less likely to help
Patients who do not use e-cigarettes or those who are not interested in nicotine consumption will not benefit from this research.
What this research studies
This research investigates the real-world impact of nicotine content in e-liquids on users' exposure to harmful substances. By monitoring 120 e-cigarette users in their natural environments for one week, the study will collect data on nicotine consumption and health effects through various biomarkers. The research aims to compare the exposure levels of users who choose lower nicotine e-liquids versus those who opt for higher nicotine options, providing insights into public health implications. The methodology includes advanced monitoring techniques and analysis of both traditional and novel measures of exposure.
Why it matters
Potential benefit: If successful, this research could lead to better regulatory policies that help reduce harmful exposure for e-cigarette users.
How similar studies have gone: Previous research has shown that monitoring real-world usage patterns can provide valuable insights into exposure levels, suggesting this approach has potential for success.
Where this research is happening
-
Rochester Institute of Technology
Rochester, United States Active
Researchers
- Principal investigator: Robinson, Risa Jean — Rochester Institute of Technology
- Study coordinator: Robinson, Risa Jean
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.