NIH-funded research R21 grant

Understanding how different factors affect individual responses to brain stimulation

Official title: Identifying the multi-modal factors that determine individual response to tDCS

Funded at Children's Research Institute · NIH-11114926 · Data updated 2026-11-12

This study is looking at how a gentle brain stimulation technique called tDCS can be customized to help people recover from strokes and manage developmental disorders, while also checking how their brains respond during the treatment.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionChildren's Research Institute
NIH-funded
Lab location1 site (Washington, United States)
Project startApril 1, 2025
Project endMarch 31, 2027
Funding year2025
Award (this year)$498,429
NIH project number1R21MH140296-01
Project IDNIH-11114926 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include adults over 21 years old who have experienced a stroke or have neurodevelopmental or psychiatric conditions.

Less likely to help

Patients who are under 21 years old or do not have conditions related to stroke, autism, or psychiatric disorders may not benefit from this research.

What this research studies

This research investigates how transcranial direct current stimulation (tDCS) can be tailored to improve outcomes for individuals with various clinical conditions, such as post-stroke recovery and neurodevelopmental disorders. By using advanced neuroimaging techniques like functional MRI, the study aims to identify the factors that influence how different people respond to tDCS treatment. Participants will undergo tDCS while their brain activity is monitored, allowing researchers to gather data on performance changes and brain connectivity. The goal is to better understand the variability in treatment responses to enhance the effectiveness of tDCS for diverse patient populations.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective tDCS treatments for patients with conditions like stroke, autism, and schizophrenia.

How similar studies have gone: Previous research has shown promising results with tDCS in various clinical settings, indicating that this approach has potential for significant advancements in treatment.

Where this research is happening

  • Children's Research Institute
    Washington, United States
    Active

Researchers

  • Principal investigator: Stoodley, Catherine J. — Children's Research Institute
  • Study coordinator: Stoodley, Catherine J.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.