Understanding how different cancer cell states affect tumor growth
Definition and perturbation of cell-regulatory heterogeneities in solid tumors
['FUNDING_OTHER'] · UNIVERSITY OF VIRGINIA · NIH-10909268
This study is looking at how different cancer cells in breast tissue behave and change, using special techniques to see them up close, with the hope of finding better ways to treat cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF VIRGINIA (nih funded) |
| Locations | 1 site (CHARLOTTESVILLE, UNITED STATES) |
| Trial ID | NIH-10909268 on ClinicalTrials.gov |
What this research studies
This research investigates the variations in regulatory states of cancer cells, particularly focusing on breast epithelial cells. By utilizing advanced techniques like laser-capture microdissection and 3D cell culture, the study aims to monitor and analyze these single-cell states in their natural environment. The goal is to uncover insights that could lead to more effective cancer treatments by understanding how these variations contribute to tumor progression. The research also involves training students in cutting-edge methodologies to further enhance cancer biology knowledge.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with breast cancer, particularly those whose tumors exhibit heterogeneity in cell states.
Not a fit: Patients with non-cancerous conditions or those with cancers unrelated to breast epithelial cells may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more targeted and effective therapies for breast cancer patients.
How similar studies have performed: Previous research using similar methodologies has shown promise in understanding cancer biology, indicating that this approach could yield valuable insights.
Where this research is happening
CHARLOTTESVILLE, UNITED STATES
- UNIVERSITY OF VIRGINIA — CHARLOTTESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, LIXIN — UNIVERSITY OF VIRGINIA
- Study coordinator: WANG, LIXIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Biology, Cancers