Understanding how different cancer cell groups work together in lung cancer spread
Deconstructing cellular heterogeneity and subpopulation cooperation in non-small cell lung cancer metastasis
This study is looking at how different types of lung cancer cells work together to spread in the body, with the hope of finding new ways to stop this process and improve treatment for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10918073 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between different subpopulations of lung cancer cells during metastasis, which is the spread of cancer to other parts of the body. By using advanced techniques like live-cell confocal microscopy and fluorescence-activated cell sorting, the researchers aim to uncover how these cells communicate and cooperate to invade tissues and survive. The goal is to identify the molecular mechanisms that enable these cancer cell groups to function as a cohesive unit, which could lead to new therapeutic strategies to combat metastasis.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with non-small cell lung cancer, particularly those experiencing or at risk of metastasis.
Not a fit: Patients with early-stage lung cancer that has not metastasized may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of targeted therapies that effectively prevent or treat metastatic lung cancer.
How similar studies have performed: Previous research has shown promise in understanding cancer cell interactions, but this specific approach to studying collective invasion in lung cancer is relatively novel.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Mouw, Janna K — Emory University
- Study coordinator: Mouw, Janna K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.