Understanding how different brain regions work together for decision-making
P5: Mechanistic Multi-Region Brain Models
['FUNDING_OTHER'] · PRINCETON UNIVERSITY · NIH-10900690
This study is looking at how different parts of the brain work together when we make complicated decisions, and it could help people understand and improve their thinking skills if they have trouble making choices.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PRINCETON UNIVERSITY (nih funded) |
| Locations | 1 site (Princeton, UNITED STATES) |
| Trial ID | NIH-10900690 on ClinicalTrials.gov |
What this research studies
This research investigates the roles of various brain areas in complex decision-making processes. By utilizing experimental data from multiple projects, the team aims to create detailed models that explain how regions like the basal ganglia and entorhinal cortex interact during evidence accumulation and decision-making tasks. Patients may benefit from insights gained about cognitive functions and potential treatments for decision-making impairments. The approach combines advanced computational modeling with experimental neuroscience to explore brain function.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit are individuals experiencing cognitive impairments or decision-making difficulties.
Not a fit: Patients with no cognitive impairments or those not involved in decision-making processes may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of cognitive disorders related to decision-making.
How similar studies have performed: Other research has shown success in understanding brain functions through similar multi-region modeling approaches, indicating a promising avenue for this investigation.
Where this research is happening
Princeton, UNITED STATES
- PRINCETON UNIVERSITY — Princeton, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOLDMAN, MARK S — PRINCETON UNIVERSITY
- Study coordinator: GOLDMAN, MARK S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.